Welcome to the latest installment of “Sight Lines,” a feature in which J.C. Noreika, MD, MBA, an ophthalmologist in Medina, OH, discusses trends in ophthalmology, medicine, and health care with key leaders in their fields. In this issue, Dr. Noreika talks with U.S. Sen. Sherrod Brown (D-OH).
Novaliq GmbH has reported positive phase I results with its clear cyclosporin solution eye drop formulation (CyclASol) in clinical development for patients with dry eye syndrome.
Valeant Pharmaceuticals International’s wholly owned subsidiary, Bausch + Lomb, and Nicox S.A. have announced positive top-line results from the pivotal phase III studies conducted with latanoprostene bunod (Vesneo, previously known as BOL-303259-X and NCX 116) for the reduction of IOP in patients with glaucoma or ocular hypertension.
Bausch + Lomb’s next-generation sub-micron gel formulation of loteprednol etabonate has been found to be statistically superior to placebo (vehicle gel) in eliminating inflammation and pain following cataract surgery by study day 8—the primary endpoints in the first phase III, multicenter, double-masked, vehicle-controlled, parallel-group study.
The FDA has approved Alimera Sciences’ fluocinolone acetonide intravitreal implant (Iluvien) for the treatment of diabetic macular edema (DME) in patients who have been previously treated with a course of corticosteroids and did not have a clinically significant rise in IOP.