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Aldehyde dehydrogenase implicated in mucous membrane pemphigoidPreliminary studies suggest disulfiram could aid in the treatment of mucous membrane pemphigoid (MMP). Used topically, the drug may inhibit aldehyde deydrogenase (ALDH), which plays a key role in fibrosis, wrote JK Dart, UCL Institute of Ophthalmology, London.
Evidence weak for blue light-filtering IOLsOnly weak evidence supports the use of IOLs that filter visible blue light, researchers say. “On the basis of currently available evidence, one cannot advocate for the use of blue-light-filtering IOLs over UV-only filtering IOLs,” wroite X. Li, Waterford Institute of Technology, Waterford, Ireland, and colleagues.
No sign of chloramphenicol resistance in bacterial conjunctivitisChloramphenicol remains effective against Gram-positive bacteria, the most common agent in bacterial conjunctivitis, researchers say.
Autoantibodies may serve as glaucoma biomarkersThe loss of autoantibodies may serve as useful biomarkers for glaucoma, according to Nadine von Thun Und Hohenstein-Blaul, Johannes Gutenberg University Mainz, Mainz, Germany, and colleagues.
Global diabetes epidemic must not become epidemic of blindnessThe global epidemic in type 2 diabetes mellitus is of unprecedented proportions. In absolute numbers, it probably exceeds any previous epidemic in the history of mankind. There are now more than 400 million people with diabetes in the world, and the number is projected to exceed 600 million by 2030.
Improving vision with electronic retinal implantsElectronic retina implants can restore enough vision for some patients to pursue tasks of daily living, according to RE MacLaren, part of a team testing the devices.
In vivo confocal microscopy ineffective for Fusarium and Aspergillus differentiationIt’s very hard to tell the difference between Fusarium and Aspergillus species with in vivo confocal microscopy (IVCM) of fungal keratitis, researchers say.
Protein fluorescence explored for cataract diagnosis
Protein fluorescence explored for cataract diagnosisFluorescence of lens proteins could help understand, diagnose, and treat cataracts, researchers say. “Rather than waiting for the condition to appear, it could be possible to diagnose and monitor cataract before it forms, allowing preventative measures to be taken where possible,” said Rory Duncan of Heriot-Watt University in Edinburh, United Kingdom in a press release.
Argon laser iridoplasty effective in occludable eyes treated with iridotomyArgon laser peripheral iridoplasty (ALPI) significantly widens the anterior chamber angle circumferentially in eyes with occludable angles treated with laser peripheral iridotomy, researchers say.
‘Real-world’ ocriplasmin macular hole closure rates lag trialsOcriplasmin (Jetrea, ThromboGenics) may achieve lower macular hole closure rates than in trials, new British and Irish data suggests. Also, “the incidence of adverse events was greater than previously reported,” wrote RJ Haynes of Bristol Eye Hospital in Bristol, United Kingdom, and colleagues in the journal Eye.

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