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Cheryl Guttman Krader
Challenges, opportunities arise
The world of glaucoma management in 2012 is feeling the impact of not only a variety of challenges, but also new opportunities.
Studies support targeting IOP
Results from randomized controlled clinical trials investigating populations covering the spectrum from ocular hypertension to advanced glaucoma provide clear evidence that for most patients, glaucoma is an IOP-sensitive optic neuropathy for which lowering IOP is effective in slowing or arresting progression.
OSST may lower melt-related complications
Results from a retrospective study suggest that prior ocular surface stem-cell transplantation (OSST) in eyes with cicatrizing disease can reduce the risk for melt-related complications following implantation of the type I Boston keratoprosthesis (Boston KPro), according to Clara C. Chan, MD.
Biometry, IOL power formulae improve outcomes
Accuracy of IOL power calculation can be significantly increased through the use of a low-coherence laser interferometry device (Lenstar LS900, Haag-Streit) for optical biometry combined with a last-generation, four-variable, "paraxial" ray-tracing formula (Olsen formula; PhacoOptics software, IOL Innovations). The benefit is due to improved prediction of postoperative IOL position, said Thomas Olsen, MD.
Transcleral or endoscopic cyclophotocoagulation support glaucoma therapy
Results from a retrospective review of outcomes after transcleral or endoscopic cyclophotocoagulation for a variety of glaucoma conditions provide additional information on the efficacy and safety of these procedures, including in select subgroups composed of eyes with either neovascular glaucoma or better than count fingers vision.
Lens now has better safety profile
Data from patients with the V4 model of the posterior chamber, foldable collagen copolymer phakic IOL implanted show that it provides excellent refractive and visual results, and, thanks to design modifications, a safety profile that is favorable, at least over the short term.
Novel bandage undergoing study
The FDA has granted IDE approval to Ocular Therapeutix to conduct a pivotal clinical trial investigating its proprietary synthetic ocular hydrogel polymer bandage for covering clear corneal incisions after cataract surgery.
Study compares drainage devices
Interim results after 2 years of follow-up in the Ahmed Versus Baerveldt Study provide prospective evidence that aqueous drainage devices may be effective treatments for refractory glaucoma, and demonstrate the advantages and disadvantages of each.
Corneal ulcers respond to corneal collagen crosslinking therapy
Results from patients treated for refractory ulcers due to infectious keratitis show corneal collagen crosslinking is an effective intervention that results in rapid and complete healing.
Study results tend to favor WFG for hyperopic LASIK
Early results from a pilot study comparing wavefront-guided (WFG) and wavefront-optimized (WFO) techniques for hyperopic LASIK show excellent safety and predictability for both, but also some differences between groups that consistently favor the WFG procedure, reported co-investigators Anthony C. Liu, MD, and Edward E. Manche, MD.


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