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Cheryl Guttman Krader
Second pivotal trial confirms IOP-lowering efficacy of first-in-class agent
Results from a second pivotal trial investigating latanoprostene bunod 0.024% (LBN) are consistent with another identically designed study showing that not only is LBN non-inferior to timolol maleate 0.5% for lowering IOP, but it has significantly greater efficacy.
Gene-based treatment provides sustained AMD therapy
The first clinical trial of lentiviral gene therapy in ophthalmology met its primary objective, demonstrating safety and tolerability of subretinal administration of a lentiviral vector expressing anti-angiogenic proteins in patients with advanced exudative age-related macular degeneration.
Exploring lens regeneration after cataract surgery
Functional lens regeneration was achieved in infants undergoing surgery for congenital cataract using a novel minimally invasive technique that maintains lens capsule integrity and preserves lens epithelial stem cells.
Managing unilateral aphakia with refractive lenticule implantation
Refractive lenticule implantation is providing good results as a technique for managing unilateral aphakia.
Femto-CKT procedure shows promise for keratoconus stabilization
Keratoconus in eyes with stage I or II disease has remained stable during follow-up to 2 years after circular keratotomy performed using a femtosecond laser.
Laser capsulotomy studies affirm low rate of anterior capsule tears
An analysis including almost 3,000 eyes operated on with modern femtosecond laser technology found an anterior capsule tear rate of <0.1%.
Switch to laser cataract surgery optimizes outcomes
Making the switch to laser cataract surgery proved beneficial for one surgeon, who experienced improvements to his LASIK enhancement rate, refractive accuracy, and visual acuity outcomes.
How lid therapy relieves obstructive MGD
Obstructive meibomian gland dysfunction is a common cause of dry eye disease. Performing lid massage using a specialized forceps improves meibum secretion with corresponding improvements in dry eye-related signs and symptoms.
Novel imaging technique characterizes aqueous outflow
Aqueous angiography is being developed as a real-time imaging technique for studying aqueous outflow.
Surgeons favor dual-linear foot pedal for efficiency in difficult cases
A survey of cataract surgeons operating with a proprietary phacoemulsification unit explored their use of dual-linear foot pedal control of fluidics and phacoemulsification power.


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