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Cheryl Guttman Krader
Re-bubbling cases show a higher endothelial cell loss post-DMEK
Analyses of data from 293 eyes undergoing uncomplicated Descemet membrane endothelial keratoplasty (DMEK) show that endothelial cell loss is greater in eyes that undergo a single re-bubbling for graft separation. The study, however, does not establish a causal association.
New dry eye treatment demonstrates rapid onset symptomatic relief
Results from the Phase 3 OPUS-3 trial provide evidence confirming a benefit of lifitegrast ophthalmic solution 5.0% (Xiidra, Shire) for significantly improving dry eye disease-related symptoms, as measured by Eye Dryness Score.
Vectored thermal pulsation delivers long-lasting MGD improvement
Follow-up from a study enrolling 200 patients with meibomian gland dysfuction showed a single treatment with vectored thermal pulsation afforded improvements in symptoms and meibomian gland function.
Toric trifocal IOL brings expanded range of functional vision to larger patient population
Toric trifocal IOL brings expanded range of functional vision to larger patient population
Trifocal IOLs can provide good uncorrected vision at near, intermediate, and far. Outcomes in a series of 30 patients show that a toric version of a trifocal IOL (AT Lisa tri 939MP, Carl Zeiss Meditec) delivers those benefits for patients with > 1 D of corneal astigmatism.
Study: Surgery for UUI outperforms medication
Bilateral replacement of the uterosacral ligaments with a polyvinylidene fluoride (PVDF) mesh (DynaMesh, FEG Textiltechnik mbH) is more effective than medical treatment with solifenacin (Vesicare) for achieving continence in women with urgency urinary incontinence (UUI) associated with only minor pelvic organ prolapse, according to the interim results of a prospective, randomized, crossover clinical trial.
Hypogonadism raises cuff erosion risk in AUS patients
Hypogonadism in men undergoing artificial urinary sphincter (AUS) implantation significantly increases the risk of cuff erosion, according to the results of a study presented by urologists from UT Southwestern Medical Center, Dallas.
Beware of nutritional supplements for kids
Sales of nutritional supplements continue to rise, and available data indicate that use of these products is fairly common within the pediatric population.
Limp raises suspicion for juvenile arthritis
There are a number of entities to consider in the differential diagnosis when a child presents with a limp, including autoimmune diseases, musculoskeletal disorders, infection, and cancer. Here's why juvenile arthritis is high on the list.
Evaluation for early puberty: When, why, and how
A workup is indicated for a child with signs of puberty starting before the normal lower age limits to determine whether the developmental changes represent normal variation or a pathologic process.
Evaluate thyroid nodules for possible cancer
Thyroid cancer is one of the most frequently diagnosed cancers in pediatric patients. Here's practical information on diagnosing and managing a child with new thyroid nodules.


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