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Cheryl Guttman Krader
ILM removal increases ease, safety of subretinal injections
Removing a small area of internal limiting membrane at the intended site of a subretinal injection allows the injection to be delivered without penetrating the retina.
Melanoma staging updates
The American Joint Committee on Cancer (AJCC) 8th Edition Melanoma Staging System includes important changes pertaining to T1 melanomas. The role of sentinel lymph node biopsy (SLNB) continues to evolve, particularly for thin melanomas. A contemporary international dataset is being applied to develop sophisticated and accurate personalized prognostic tools.
Does FLACS cost, benefit outweigh manual? Yes!
Though further study is needed to determine conclusively whether or not femtosecond laser-assisted cataract surgery (FLACS) is associated with better refractive outcomes compared with conventional manual surgery, FLACS offers many other benefits that justify its use, according to Robert J. Cionni, MD.
Does FLACS cost, benefit outweigh manual? No!
Femtosecond laser-assisted cataract surgery (FLACS) offers some advantages compared with a conventional manual procedure, particularly for certain patients. Currently, however, FLACS does not result in superior outcomes and it has drawbacks that outweigh its benefits, according to Rosa Braga-Mele, MD.
Redesigned pupil expansion device reduces cataract surgery risks
Pre-treatment with the femtosecond laser in eyes undergoing cataract surgery can induce miosis. The use of a pupil expansion device, however, offers an effective method for managing small pupils in femtosecond laser-assisted cases whether the problem pre-exists or is caused by the laser, said Boris Malyugin, MD, PhD.
Melanoma staging updates
The American Joint Committee on Cancer (AJCC) 8th Edition Melanoma Staging System includes important changes .
Investigational wet AMD therapies aim for innovative targets
Many investigational drugs under development for the treatment of neovascular age-related macular degeneration (nvAMD) have advanced into the clinical trial stage, including several that are being evaluated in pivotal trials, said Peter K. Kaiser, MD.
Novel topical peptide for dry eye tackles underlying cause of disease
A phase I/II trial enrolling patients with Sjögrens syndrome dry eye will be investigating  a synthetic fragment of a naturally occurring tear glycoprotein. Findings from extensive laboratory and preclinical research suggest that it is a promising novel therapy.
Non-invasive punctal plug delivery system offers a host of positive performance characteristics
Non-invasive punctal plug delivery system offers a host of positive performance characteristics
A silicone punctal plug-based delivery system for ophthalmic medications (Evolute, Mati Therapeutics) provides precisely controlled medication release into the tear film and has been associated with positive results in initial clinical testing.
Exploring off-label, investigational approaches for allergic conjunctivitis
Seasonal and perennial allergic conjunctivitis are common conditions that are not always well-controlled with conventional therapy. Alternative approaches and novel investigational treatments are discussed.

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