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Lynda Charters
ALG-1001: Turning off the machinery of angiogenesis
ALG-1001 (Luminate, Allegro Ophthalmics) has a number of different mechanisms of action that benefit patients chronically treated with anti-vascular endothelial growth factor drugs and those who are treatment naïve.
Aflibercept helps in ME patients with DR after cataract surgery
Patients with diabetic retinopathy have a high risk of developing macular edema after cataract surgery. Intravitreal injections of aflibercept might result in fewer patients developing macular edema in this patient population.
OCTA system offers exquisite views
OCTA system offers exquisite views
A new high-density OCT angiography system (AngioVueHD, OptoVue) provides exquisite views of the retinal microvasculature without the need for injection of fluorescein dye.
Priming syringe before injection associated with lower frequency of silicone oil droplets
Another adverse effect associated with the compounding process of bevacizumab (Avastin, Genentech)—i.e., the presence of silicone oil droplets in the vitreous cavity—has surfaced within the past year and seems to be related to the preloading of the drug in insulin syringes.
Scleral implant for presbyopia making accommodative gains
Scleral implant for presbyopia making accommodative gains
Implantation of an investigational device for presbyopia resulted in a minimal 2-line increase in distance-corrected near visual acuity and an actual reduction in the amount of near add needed over time, show findings from a single-center, subgroup analysis.
POAG: Enigmatic group of heterogenous diseases?
Various subtypes of primary open-angle glaucoma might exist. Continued research is needed to identify the characteristics of each subtype for better management.
Frozen, fresh corneal donor carriers yield similar clinical outcomes
Five-year results from a study of the Boston keratoprosthesis type 1 implant suggest that frozen and fresh corneal donors offer similar clinical outcomes—with no significant differences in device retention, visual rehabilitation or complication rates.
CATT follow-up explores long-term outcomes with anti-VEGF in AMD
The Comparison of Age-related Macular Degeneration Treatment Trial (CATT) follow-up study found that the initial gains in visual acuity achieved with two anti-vascular endothelial growth factor drugs were lower than those achieved at the end of the 2-year CATT study.
Glaucoma risk may increase after cataract removal in early infancy
Glaucoma risk may increase after cataract removal in early infancy
Glaucoma is more likely to develop in children who undergo cataract surgery when they are 6 weeks or younger.
Dry AMD therapy evolves with photobiomodulation
Non-invasive photobiomodulation may help dry age-related macular degeneration by causing regression of drusen and improving retinal function with benefits in visual acuity and contrast sensitivity.


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