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Lynda Charters
Exploring sirolimus as potential alternative therapy for persistent AMD
Anti-vascular endothelial growth factor (VEGF) therapy is highly successful, but as Raj Maturi, MD, pointed out, also has some limitations.
SHRM characteristics impact visual acuity in wet AMD
Subretinal hyperreflective material (SHRM) is a morphologic component seen on optical coherence tomography (OCT) images as hyperreflective material that is external to the retina and internal to the retinal pigment epithelium (RPE), said Jaya B. Kumar, MD.
Persistence is key when promoting surgical innovations
A surgical innovation is defined as a quantum improvement in the treatment of a particular disease or group of diseases, and it usually is developed by an individual or a small group working together, said John Thompson, MD.
DNA-based analysis identifies risk factor for metastasis of uveal melanoma
Carol. L. Shields, MD, highlighted the results of collaborative efforts among four Philadelphia institutions: Wills Eye Hospital, Thomas Jefferson Hospital, the Genetics Department of the University of Pennsylvania, and the Wistar Instituate. The findings were published in Ophthalmology (Shields et al. 2017; published online May 7, 2017).
Unmasking retinal structure, function in X-linked retinoschisis
“There is a compelling need to explore gene therapy in the eye,” according to Paul A. Sieving, MD, PhD.
Dye from açai fruit safe, effective for use during chromovitrectomy
Dye from açai fruit safe, effective for use during chromovitrectomy
A dye made from the açai fruit (Euterpe oleracea) is safe for use in human eyes and effective for identifying the posterior hyaloid and internal limiting membrane (ILM) during vitreoretinal surgery, according to phase I preliminary study results.
Paracentral retinotomy facilitates closure of large, resistant macular hole
Recognition of this problem resulted in an innovative approach for closing persistent macular holes after the primary surgery has failed by creating a separate paracentral retinotomy in the nasal macula. Michael S. Tsipursky, MD, described the rationale for trying this treatment approach. “
Reduced risk of CNV after SDM laser retinal protective therapy
The dry form of age-related macular degeneration (AMD) is the most common type of the disease, but successful treatments have been elusive in patients, resulting in disease progress and visual loss.
Natamycin still the best bet for fungal keratitis
A recent study sponsored by the National Eye Institute (NEI) of the optimal treatments for fungal keratitis showed that topical natamycin is still the mainstay of treatment. Adding oral voriconazole to the treatment regimen also may be beneficial to treat patients with Fusarium species.

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