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Lynda Charters
Targeting TGF-beta in different ocular diseases
A potent and selective transforming growth factor (TGF)-β2 LNA-modified antisense oligonucleotide induces biologic responses consistent with the drug’s expected molecular mechanism of action in different preclinical ocular surface disease models.
Cutting-edge LASIK technologies in quest for perfect vision
Take-home message: The various excimer ablation technologies have their pros and cons. Wavefront-guided ablations using aberrometry can provide the vast majority of patients with uncorrected vision of 20/20 with fewer postoperative visual symptoms.
Referral criteria trumps screening technology for amblyopia
Physicians should focus on referral criteria in screening technology rather than the instrument itself.
Combo therapy improves VA in AMD patients
Anti-vascular endothelial growth factor (anto-VEGF) monotherapy is inadequate in patients with age-related macular degeneration (AMD). However, by adding an anti-platelet-derived growth factor (anti-PDGF) drug to the anti-VEGF regimen, treatment is enhanced by preventing the development of fibrosis thus improving visual outcomes, according to Usha Chakravarthy, MBBS, PhD.
Dropless cataract surgery yields postoperative prophylaxis for patients, practices
Dropless cataract surgery—a combination of anti-infective and anti-inflammatory drugs injected transzonularly or through the pars plana for deposit into the vitreous—reduces the need for topical postoperative drops.
Novel metric may determine ectasia risk
Using a new metric seems to be an easy way to determine a patient’s risk of developing ectasia after a refractive procedure, according to Marcony R. Santhiago, MD, PhD.
High-res device gives retinal imaging a facelift
Retinal disease has been given a new face thanks to increased details of the adaptive optics scanning laser ophthalmoscope (AO-SLO), according to Mina Chung, MD.
Novel accommodative IOL shows stable visual function over 18 months
Fluid-based accommodating IOL technology achieved “true accommodation” in a pilot study. A multicenter study of the lens is ongoing.
Defending adjustable sutures in strabismus surgery
It may be easier than ever for strabismus surgeons to adopt adjustable sutures thanks to a short tag noose adjustable suture technique that allows for optional suture adjustment, according to David G. Hunter, MD, PhD.
Intravitreal bevacizumab: Improved vascular pattern after treatment in ROP
After intravitreal bevacizumab injection in eyes with treatment requiring-retinopathy of prematurity, there was growth and maturation of retinal vessels, although certain abnormalities remained.

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