| | Ptosis: A sign of myasthenia gravis
| | Ptosis is a sign of a number of diseases, most of which are benign. Julie Falardeau, MD, of the Casey Eye Institute, Portland, OR, described how ophthalmologists can avoid overlooking myasthenia gravis, which can be associated with serious morbidity and mortality. | |  |
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| Giant cell arteritis: An updated review
| | Ophthalmology Times | | This article summarizes the recent elucidations on the immunopathogenic process that leads to giant cell arteritis (GCA) and reviews both the well-known and newly recognized clinical subtypes and manifestations of the disease. The role of various noninvasive imaging techniques that are increasingly used to corroborate a clinical diagnosis of GCA as well as traditional and new treatment strategies are discussed. |
| | Cell loss, retinal thinning found after excitotoxic damage
| Findings suggest axonal damage and excitotoxicity may be related, possibly through genetic connection
| | Ophthalmology Times | | A study in a rat model found retinal ganglion cell loss and retinal thinning following excitotoxic damage. This finding has led researchers to speculate that axonal damage and excitotoxicity are related, and that the connection may be through the Wallerian degeneration gene. Future research into this pathway could lead to new forms of treatment for glaucoma and other neurologic diseases. |
| | Genomic rearrangements in OPA1 gene frequent in adOA
| Patients with autosomal dominant optic atrophy show aberrations on MLPA testing
| | Ophthalmology Times | | Multiplex ligation probe amplification (MLPA), a relatively new technique for detecting copy number variations in genomic sequences, has been used to study the pathomechanism of autosomal dominant optic neuropathy. |
| | Supranuclear gaze disturbances can be confusing
| Here's what the general ophthalmologist needs to know
| | Ophthalmology Times | | Supranuclear gaze palsy should be suspected in patients with bilateral and symmetric vertical or horizontal gaze difficulty. Use of specific maneuvers to bypass the supranuclear input to the ocular motor nuclei can help to establish a supranuclear localization to the problem and direct neuroimaging to the supranuclear pathways in the brain and brainstem. |
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| Ptosis: A sign of myasthenia gravis
| | Ophthalmology Times Meeting E-News | | Ptosis is a sign of a number of diseases, most of which are benign. Julie Falardeau, MD, of the Casey Eye Institute, Portland, OR, described how ophthalmologists can avoid overlooking myasthenia gravis, which can be associated with serious morbidity and mortality. |
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