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Ophthalmology

DNA-based analysis identifies risk factor for metastasis of uveal melanomaCarol. L. Shields, MD, highlighted the results of collaborative efforts among four Philadelphia institutions: Wills Eye Hospital, Thomas Jefferson Hospital, the Genetics Department of the University of Pennsylvania, and the Wistar Instituate. The findings were published in Ophthalmology (Shields et al. 2017; published online May 7, 2017).
Unmasking retinal structure, function in X-linked retinoschisis“There is a compelling need to explore gene therapy in the eye,” according to Paul A. Sieving, MD, PhD.
Dye from açai fruit safe, effective for use during chromovitrectomy
Dye from açai fruit safe, effective for use during chromovitrectomyA dye made from the açai fruit (Euterpe oleracea) is safe for use in human eyes and effective for identifying the posterior hyaloid and internal limiting membrane (ILM) during vitreoretinal surgery, according to phase I preliminary study results.
Paracentral retinotomy facilitates closure of large, resistant macular holeRecognition of this problem resulted in an innovative approach for closing persistent macular holes after the primary surgery has failed by creating a separate paracentral retinotomy in the nasal macula. Michael S. Tsipursky, MD, described the rationale for trying this treatment approach. “
B+L next-generation surgical platform features advanced retina capabilities
Laser retains limited role for management of RVO-related MEIn the current era where pharmacologic therapy is the preferred treatment for macular edema secondary to retinal vein occlusion (RVO), there is still a role for laser, according to Francesco Bandello, MD.
OCTA brings understanding to managing diabetic eye diseaseOptical coherence tomography angiography (OCTA) is a promising new approach for visualizing retinal vascular pathology in eyes with diabetic eye disease that can be expected to have even greater utility in the future pending further enhancements.
Anti-angiogenic agent, platform planned for human trialFindings from preclinical studies show that a novel intravitreal depot of an anti-angiogenic drug releases the medication over a period of at least 6 months, is well-tolerated, and prevents VEGF-induced retinal vascular leakage.
Scleral buckle technique using PPV, laser photocoagulation
Scleral buckle technique using PPV, laser photocoagulationScleral buckles and vitrectomy are the two main procedures used today to treat retinal detachments, with many surgeons performing a combination of the two.
Retinectomy-under-air solution for retina reattachment
Retinectomy-under-air solution for retina reattachmentIn complicated retinal detachment cases where the retina fails to reattach after completing the usual steps, retinectomy is a better technique than relaxing retinotomy–and the retinectomy is best done incrementally under air, said Steve Charles, MD.