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    Regeneron, Avalanche collaborate on gene therapy

    Orlando—Regeneron Pharmaceuticals and Avalanche Biotechnologies announced a collaboration to discover, develop, and commercialize novel gene therapy products for the treatment of ophthalmologic diseases.

    The collaboration covers novel gene therapy vectors and proprietary molecules—discovered jointly by Avalanche and Regeneron—and developed using the Avalanche Ocular BioFactory, an adeno-associated virus-based, proprietary, next-generation platform for the discovery and development of gene therapy vectors for ophthalmology.

    Under the terms of the agreement, Avalanche will receive an upfront cash payment, contingent payments of up to $640 million upon achievement of certain development and regulatory milestones, plus a royalty on worldwide net sales of collaboration products.

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