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    Sustained drug delivery moving toward clinical use


    Amorphex Therapeutics

    The topical ophthalmic drug delivery device (TODD) is a soft elastomer drug depot that floats atop the sclera under the eyelid. It can be inserted or removed as easily as a contact lens with none of the problems associated with soft contact lenses that dry out or collect deposits.

    “We are delivering therapeutic doses of drug, but without any of the systemic exposure you get from eye drops,” said Robert Thompson, president and CEO. “You can deliver multiple drugs at multiple rates of release with a single device. In all of the testing we have done on animals and human subjects, we have never seen any detectable amount of drug in the blood.”

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