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    Transepithelial PRK safe, effective at one year


    Examining the study

    Dr. Kim and his colleagues treated 381 eyes of 159 patients with a mean age of 27.2 years. The cohort included 68 males and 91 females. The mean preoperative spherical refraction was -4.12 D, the mean cylindrical refraction was -0.63 D, and the corrected visual acuity was 20/20 or better for all patients.

    Patients with corneal epithelial pathology, keratoconus, ocular inflammation, glaucoma, or posterior segment pathology were excluded from the study.

    All patients received mitomycin-C (0.01% for 10 to 25 seconds), a soft bandage contact lens for 3 to 4 days as needed, topical levofloxacin 4 times daily for 2 weeks, and fluorometholone (0.1%) 6 times daily after epithelial closure, and tapered over 3 to 4 months.

    Postoperative pain was assessed by patient report and epithelial healing was evaluated by daily slit-lamp exam until the re-epithelialization was complete. Uncorrected visual acuity, best corrected visual acuity, remaining refractive error, and corneal haze were evaluated at 3 or 4 days, 3 weeks, 2 months, 6 months and 12 months following surgery.


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