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    Improving LASIK outcomes: Addition of CXL for corneal stability

    Theoretical, practical applications explored in wound healing, biomechanical changes after wavefront-guided surgery



    Achieving super-vision after LASIK may rest on the addition of corneal collagen crosslinking around the time of surgery.


    ChicagoOphthalmologists are faced with wound healing and biomechanical changes after wavefront-guided keratorefractive surgery that include mechanical complications related to flap creation in LASIK and optical complications related to decentration, optical zone size, positive asphericity, and uncorrected higher-order aberrations (HOAs).

    Despite advances in laser technology—such as iris registration, multifocal ablations, mixed astigmatism, intraoperative pachymetric monitoring, and the introduction of femtosecond laser technology—the complications related to customized LASIK remain. These include flap complications, custom cornea limitations, and ectasia.

    The answer to these problems may be the addition of corneal collagen crosslinking (CXL) performed around the time of LASIK, according to Dimitri T. Azar, MD, MBA, dean, University of Medicine, holder of the B.A. Field Chair in Ophthalmologic Research, and professor of ophthalmology, pharmacology, and bioengineering, University of Illinois at Chicago.

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