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    Corneal crosslinking shows favorable long-term outcomes

    Study examined CXL using Dresden protocol for the treatment of progressive keratectasia


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    Studies with follow-up of 2 to 6 years show that corneal crosslinking for progressive keratectasia is safe and induces long-term structural changes.


    Dr. Seiler

    Zurich, Switzerland—Results from 5 years of follow-up support the efficacy and safety of corneal crosslinking (CXL) using the original Dresden protocol for the treatment of progressive keratectasia, said Theo Seiler, MD, PhD, who pioneered the procedure.

    The data, Dr. Seiler said, shows that CXL results in a significant keratometric flattening effect that is stable in most eyes, while causing minimal complications or significant best spectacle-corrected visual acuity (BSCVA) loss.

    “CXL induces structural changes in the cornea that may continue for many years,” said Dr. Seiler, professor of ophthalmology, University of Zurich, and Chairman, IROC Zurich, Switzerland. “However, do not forget that (these) long-term results . . . are based on treatment with the Dresden protocol using an epithelium-off technique.

    “They may not apply to epithelium-on and other procedures,” he added.


    Cheryl Guttman Krader
    Cheryl Guttman Krader is a contributor to Dermatology Times, Ophthalmology Times, and Urology Times.

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