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    Hydrogel punctal plugs safe, viable means for sustained drug delivery

    Fluorescein aids visualization, allowing physicians and patients to monitor presence


    The investigators concluded that the hydrogel punctal plug platform may be a safe and viable means for achieving sustained drug delivery.

    “Numerous studies have demonstrated this, including non-drug plug studies and various drug-eluting plug studies,” he said. “Fluorescein conjugated with polyethylene glycol in the punctal plugs gives physicians and patients the ability to monitor the presence of the plugs for durations of therapy.

    “Hydrogel punctal plugs may be a useful alternative to topical drop therapy to circumvent patient non-compliance in chronic conditions, such as glaucoma,” he added. 


    Robert J. Noecker, MD

    E: [email protected]

    This device is investigational and not yet available commercially in the United States. The study was sponsored by Ocular Therapeutix. Dr. Noecker is a paid consultant, received research support, and has a financial interest in the company.



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