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    Approaching corneal erosion treatments


    Buffalo, NY—There are a number of therapeutic options available for managing eyes with recurrent corneal erosion (RCE) syndrome, and a treatment algorithm developed by James J. Reidy, MD, prioritizes their use based on lesion characteristics.

    “Many treatments have been described for eyes with RCE syndrome, and most work well, with an average success rate of about 75%,” said Dr. Reidy, clinical professor of ophthalmology, The State University of New York School of Medicine & Biomedical Sciences, Buffalo. “However, no one treatment is effective 100% of the time nor stands head and shoulders above the rest.”

    The first step in the treatment algorithm divides lesions based on whether they are microform or macroform erosions. To manage microform erosions representing a first episode, Dr. Reidy said he begins conventional therapy with topical lubrication using artificial tears during the day and an ointment (5% hypertonic saline, preservative-free lubricant) at night. For recurrent microform erosions, he prescribes oral doxycycline for 60 days combined with a mild topical corticosteroid for 2 to 3 weeks.

    “This combination of oral and topical anti-inflammatory treatment was first described by Dursun al. in 2001, and it has had a dramatic benefit in my practice for decreasing the need for surgical intervention,” Dr. Reidy said.

    Cheryl Guttman Krader
    Cheryl Guttman Krader is a contributor to Dermatology Times, Ophthalmology Times, and Urology Times.

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