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    AD-IOLs mimic movement of natural lens

    Novel concept for accommodating IOLs captures, transforms zonular movement into axial shift

    Take-home message: Accommodating-disaccommodating IOLs are being developed that mimic the movement of the young crystalline lens through the use of “Zonular Capture Haptics” technology.

    Reviewed by Paul M. Beer, MD

    St. Petersburg, FL—Almost a decade ago, Paul M. Beer, MD, set out to develop a pseudophakic IOL for in-the-bag implantation that would replicate the movement of the young crystalline lens. 

    At the XXXIV Congress of the European Society of Cataract and Refractive Surgeons in Copenhagen last month, Dr. Beer reported on his success using “Zonular Capture Haptics” (ZCH) to create accommodating-disaccommodating IOLs (AD-IOLs).

    Related: Unique approach to managing a posteriorly dislocated IOL

    Courtesy of Paul M. Beer, MD

    Two AD-IOL prototypes are in development. The first is based on axial shift of a single foldable monofocal optic that would meet FDA label requirements. It has been implanted in six animal eyes so far, demonstrates continued efficacy after more than 1 year of follow-up, and is ready for resizing for human eyes.

    The second, which is at an early prototype stage, is a dual mode AD-IOL that combines axial shifting and optic shape changing mechanisms. Based on “in silico” studies, the dual mode implant is estimated to produce 10 to 14 D of accommodation. Preclinical animal studies are targeted to begin in the first quarter of 2017.

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