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    Advanced wavefront-guided LASIK corresponds with positive patient-reported outcomes


    Analyses of data collected in U.S. FDA trials of wavefront-guided LASIK for myopia and mixed astigmatism using a new high-definition aberrometer (STAR S4 IR Laser System/iDESIGN AWS System, Johnson & Johnson Vision) show that treated patients benefit with significant improvements in visual functioning and well-being and are doing better than a population that has not undergone refractive surgery, said Daniel S. Durrie, MD.

    “In the field of excimer laser refractive surgery, the traditional endpoints have been based on assessments of uncorrected visual acuity, refractive predictability and stability, and higher-order aberrations,” said Dr. Durrie, clinical professor and director of refractive surgery services, University of Kansas Medical Center, Kansas City.

    However, there is a big focus on patient-reported outcomes for determining the value of a new modality. When it comes to LASIK, patients care about how they see and not about the parameters we typically measure, he noted.

    “Ophthalmologists who have been in this field for a while are used to having patients complaining about some things being worse after surgery than before,” Dr. Durrie said. “With advances in our technologies, we seem to be moving in the right direction.”

    The study for myopia was performed at 12 sites; 8 sites participated in the study for mixed astigmatism. The myopia study enrolled eyes with up to -11.0 D spherical equivalent and up to -5.0 D cylinder as measured with the high-definition aberrometer. It included 334 eyes of 170 subjects. The mixed astigmatism study included 149 eyes of 84 patients with up to 6.0 D of cylinder.

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