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    Biosensors in contact lenses can monitor IOP and diabetes

     

    Continuous contact lens wear can also be uncomfortable, and increase the risk of microbial keratitis, contact lens peripheral ulcers, and inflammatory complications. In elderly patients, who are most often in need of this type of monitoring, the problems of intolerance and disabilities preventing contact lens insertion and removal are particularly common, Phan and colleagues noted.

    For some conditions, however, the wearer could remove the contact lens soon after insertion allowing analysis and quantification of biomarkers outside the eye. This approach could lend itself to conditions such as dry eye and cancer that don’t require continuous monitoring.

    At the same time, contact lens sensor technology faces some other significant obstacles. Tear analysis can be difficult because of variations in the tear proteome, the low concentration of biomarkers in tear film, and variations with sex, age, and time of day.

    Still, the authors noted, if these barriers can be overcome, contact lens sensors could produce immense amounts of information, leading to better effective treatments and improvements in individualised medicine.

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