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    Changing the game in treatment of acute pseudophakic CME

    Bromfenac/delivery vehicle yields high intraocular concentration, more efficacious response


    Slow taper

    Subsequently, slow taper of both  bromfenac 0.075% and difluprednate was initiated. At final follow-up exam on Jan. 20, 2017 after completion of topical therapy taper, B.L’s uncorrected vision was at 20/30- OD and complete resolution of CME was achieved with no recurrence (Figure 5).

    Of note, after refraction and new glasses, B.L. was extremely happy to achieve best-corrected vision of 20/25+2 with excellent visual outcome. I postulate that bromfenac 0.075%, with its Durasite vehicle, is able to create a much higher intraocular concentration (as compared with other topical NSAIDs)—thus resulting in a more efficacious response in the treatment of acute pseudophakic CME.

    Overall, determining the best treatment agents for pseudophakic CME remains the decision of each retinal specialist. I typically implement the combination of topical bromfenac 0.075% (BromSite) (one drop twice a day) and difluprednate (one drop four times a day) with subsequent taper once resolution of CME is demonstrated.


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    6. https://www.reviewofophthalmology.com/article/thoughts-on--cataract-surg...
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    10. http://www.bromsite.com


    Joshua Mali, MD

    P: 941/923-2020

    Dr. Mali is a board-certified ophthalmologist and vitreoretinal surgeon at The Eye Associates, Sarasota, FL. Dr. Mali has no relevant financial disclosures.

    Joshua Mali, MD
    Joshua Mali, MD, is a vitreoretinal surgeon at The Eye Associates, a private multispecialty ophthalmology practice in Sarasota, Florida.

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