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    CO2 laser-assisted surgery yields better sclerectomy for open-angle glaucoma

    Non-penetrating procedure associated with good IOP control during short follow-up

    Take-home message: CO2 laser-assisted sclerectomy surgery performed with a proprietary platform is a simple and safer alternative to manual non-penetrating deep sclerectomy for eyes with open-angle glaucoma.


    Katowice, Poland—CO2 laser-assisted sclerectomy surgery (CLASS) shows promise as a safe and effective procedure for reducing elevated IOP and medication burden in various types of glaucoma, said Edward Wylegala, MD, PhD.

    CLASS is a non-penetrating procedure in which the outer wall of Schlemm’s canal is removed using a proprietary CO2 laser (IOPtimate System, IOPtima) and the anterior chamber remains intact.

    Dr. Wylegala performed CLASS in a series of 10 eyes, of which 8 had primary open-angle glaucoma and 2 had secondary capsulary glaucoma associated with pseudoexfoliation syndrome.

    After 6 months of follow-up, mean IOP was reduced 38.4% from baseline (25.4 to 15.1 mm Hg) and mean number of medications used decreased from 3.8 to 0.3.

    At the 6-month visit, 8 eyes met the criteria for complete success (IOP between 5 and 18 mm Hg and 20% IOP reduction from baseline with no medication), and qualified success (same IOP criteria with or without medication) was achieved by all 10 eyes.

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