/ /

  • linkedin
  • Increase Font
  • Sharebar

    Confessions of an innovator

    How ophthalmic breakthroughs evolved from the bizarre to medical, surgical realities



    Addressing fungal infections

    In the 1960s, there was no cure for corneal fungal infections arising from accidents with vegetation that occurred among itinerant workers in Florida, but Dr. Kaufman knew about a substance, Pimaracin (natamycin), in use in Holland that kept cheese from getting moldy.

    He designed an animal model of a fungal infection with which he and his colleague, Emanuel Newman, proved that the substance was efficacious for treating human infection. They then provided it to clinicians for free for 2 years. This application ultimately achieved FDA approval without a clinical trial or a manufacturer. Alcon Laboratories later entered the picture and manufactured the drug.

    “Pimaracin remains the most effective drug for treating especially commonly fungus keratitis,” Dr. Kaufman said.


    Lynda Charters
    Lynda Charters is a freelance medical writer.

    New Call-to-action


    You must be signed in to leave a comment. Registering is fast and free!

    All comments must follow the ModernMedicine Network community rules and terms of use, and will be moderated. ModernMedicine reserves the right to use the comments we receive, in whole or in part,in any medium. See also the Terms of Use, Privacy Policy and Community FAQ.

    • No comments available


    View Results