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    Confessions of an innovator

    How ophthalmic breakthroughs evolved from the bizarre to medical, surgical realities



    Clinical specular microscopy

    With all the previous successes, failures were inevitable. William Bourne, MD, and Dr. Kaufman developed the clinical specular microscope and observed endothelial damage resulting from contact between IOLs and the endothelial tissue.

    To counteract this, viscous methylcellulose was used with the hope that it would provide protection for the endothelium. He evaluated and published a series of randomized cataract surgeries with and without the viscous methylcellulose and showed the degree of protection provided by the product.

    “But I failed, because I did not patent it or push it sufficiently hard and no company manufactured it,” Dr. Kaufman recounted.

    Healon was patented later as a viscoelastic.

    Lynda Charters
    Lynda Charters is a freelance medical writer.

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