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    Device makers swing for fence with new technologies



    Most MIGS devices reduce IOP by shunting aqueous within the eye. MicroOptx shunts directly the tear film. The is no bleb, encapsulation is not a problem, and episcleral venous pressure cannot cause nighttime IOP increases.

    “Our device is engineered to achieve an IOP of 8 to 10 mm Hg,” said Chief Executive Officer Chris Pulling. “Our goal is to halt progression to blindness rather than simply slowing progression to blindness.”

    More: Flying Eye Hospital aims to prevent blindness worldwide

    Implantation takes about a minute using a small stab incision, Pulling said. The actual device is about 1.5 mm wide and protrudes about 300 µm above the conjunctiva.

    The lumen is coated with a hydrophilic coating that binds with the aqueous and effectively prevents adherence by proteins, cells, or bacteria. The sheer stress from constant laminar flow inhibits any bacterial encroachment.

    Testing in pig eyes shows no infection and minimal inflammation with rapid healing. The device quickly and consistently lowers IOP from 14 to 15 mm Hg in control eyes to 8 to 10 mm Hg in test eyes.

    More: Glaucoma cure may be found in newly discovered biomarkers

    “We have a very small size, very simple design, and very low risk that produces very consistent, predictable and dramatic reductions in IOP,” Dr. Pulling said. “We will be starting our first human trials in the United States in July or August (2016).”

    New World Medical

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