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    DMEK associated with better visual quality

    Study compared functional vision outcomes of DMEK versus DSAEK

    Take-home message: A focus on functional vision outcomes in patients who had both DMEK and DSAEK procedures found that the DMEK procedure yielded quality of vision superior to that of DSAEK.



    Portland, OR—Some surgeons may see only a slight advantage in performing Descemet membrane endothelial keratoplasty (DMEK) over Descemet stripping automated endothelial keratoplasty (DSAEK), with a Snellen visual acuity difference of only about a line.

    However, that perspective does not consider functional vision outcomes, said Michael D. Straiko, MD, Devers Eye Institute, Portland, OR.

    In a study led by Dr. Straiko, patients that had DMEK in one eye and DSAEK in the fellow eye had significantly better quality of vision in the DMEK eye as evidenced by patient preference and objective measurement of contrast sensitivity. The DMEK-treated eyes had contrast sensitivity that approached that of normal eyes that had no prior surgery.

    The group had also previous published research on the topic of DSAEK versus DMEK outcomes.1

    Results showed similar results in both groups except for slightly better visual acuity in the DMEK group. It got them wondering whether visual acuity tells the full story of visual results, particularly because Snellen visual acuity is usually measured under ideal lighting and high contrast conditions, unlike real life, Dr. Straiko said.

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