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    Fibrin adhesives another approach to epithelial ingrowth post-LASIK

    Usage effective, associated with few complications


    Consider adhesives

    Another treatment alternative is hydrogel adhesive applications, Dr. Hardten said.

    One fibrin adhesive (Tisseel Fibrin Glue, Baxter) is a mix of fibrinogen and thrombin, but it also has a bovine fibrinolysis inhibitor. The product takes 8 to 10 minutes to dry so a bandage scleral contact lens can be placed; it dissolves in 10 to 14 days.

    Recent: Postop keratometry not associated with night-vision problems

    In a study that Dr. Hardten led with fibrin glue used after LASIK to treat epithelial ingrowth, there was no recurrence in 80% of eyes over an average 26 months of follow-up.1

    Thirty-nine eyes from 38 patients were included in the retrospective case series. Five eyes (12.8%) had mild epithelial ingrowth, but it did not require removal; at the 3-month follow up, three eyes (7.7%) had significant epithelial ingrowth requiring removal and fibrin application. At the final follow-up, which occurred at a little over 2 years, 84.6% of eyes had corrected distance visual acuity of 20/25 or better, and 74.4% had 20/40 or better uncorrected distance visual acuity. Ninety-two percent of eyes had unchanged or improved corrected visual acuity.

    Complicated cases

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