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    Fibrin adhesives another approach to epithelial ingrowth post-LASIK

    Usage effective, associated with few complications


    Two eyes in the study had flap amputation due to irregular astigmatism from pre-existing areas of flap melt that were still a problem; one eye had ectasia (also pre-existing) and subsequent Intacs placement (Addition Technology), and another eye had poor vision from glaucoma (also pre-existing), Dr. Hardten said.

    More: Novel forceps design improves iris hook placement

    “Any of the brands of fibrin adhesive may be a useful adjunct in epithelial ingrowth removal in complicated cases,” he said.

    These fibrin adhesives may reduce the incidence of recurrent epi-ingrowth, and they are well tolerated with no associated complications. However, larger randomized studies would be helpful to determine safety and efficacy compared with primary removal or sutures, he said.

    Dr. Hardten noted some researchers have described using hydrogel adhesives in cases that do not require as long of a time for retention of the adhesive.

    Related: More about the new-generation presbyopia-correcting IOL



    1. Hardten DR, Fahmy MM, Vora GK, Berdahl JP, Kim T. Fibrin adhesive in conjunction with epithelial ingrowth removal after laser in situ keratomileusis: long-term results. J Cataract Refract Surg. 2015;41:1400-1405.


    David R. Hardten, MD

    E: [email protected]

    This article was adapted from Dr. Hardten’s presentation during Cornea Day at the 2016 meeting of the American Society of Cataract and Refractive Surgery. Dr. Hardten has done research, consulting, or speaking for Abbott, Allergan, Calhoun Vision, CXL-USA, ESI, Humanoptics, Oculus, OSD, Quantel and TLCV. Some of the information may represent off-label uses of approved drug or devices.

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