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    How new ‘evolving’ IOL formula maximizes lens accuracy

    In the modern landscape of ophthalmology, there is an abundance of intraocular lens (IOL) calculation formulae. This often leads to a clinical dilemma when it comes to choosing the most appropriate formula. Figure 1A: Ladas Super Surface in its raw form

    Thus far, there did not exist a perfect formula for all situations, including extremities of keratometry and axial length. Since there was no “one” formula, surgeons resorted to using multiple formulae without a framework to do so.

    In developing the “Ladas Super Formula,” the first question we asked was: “How do we capture the best aspects of each formula, while minimizing their drawbacks?”

    We looked at these formulae as the algebraic equations that they were. We wondered what we could do by simply graphing these formulae into three dimensions.

    James Gleick, the author of Chaos: Making a New Science, said that “graphic images are the key” and “it’s masochism for a mathematician to do without pictures … [Otherwise] how can they see the relationship between that motion and this? How can they develop intuition?”Figure 1B: A somewhat amalgamated Ladas Super Surface

    Once we could visualize these formulae in 3-D, we decided to use this methodology to compare IOL formulae with each other, isolate them and join them together, and what we ended up with was the “Ladas Super Formula” (see Figure 1).

    Figure 1C: Fully coalesced Ladas Super Surface

    The Ladas Super Formula is a novel approach of taking the ideal portions of current IOL formulae and stitching them together to create one amalgamated surface and corresponding formula.

    (All figures courtesy of Aazim A. Siddiqui, MD)


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