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    How novel anticoagulants compare with warfarin for intraocular bleeding

    How do the newer anticoagulant medications compare with warfarin when it comes to the risk of intraocular bleeding? 

    A meta-analysis published in JAMA Ophthalmology did a systematic review of phase 3 randomized trials looking at over 100,000 patients.

    The results indicated the risk of intraocular bleeding was reduced by one-fifth with newer anticoagulants, compared with warfarin. This was especially relevant for patients with a higher risk of spontaneous retinal and subretinal hemorrhage. 

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