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    Hypochlorous acid eyelid wash reduces bacterial load

    Application did not alter diversity of bacteria recovered but can reduce symptoms related to overgrowth

    Take-home message: Researchers investigate the magnitude of bacterial load reduction on the surface of the skin 20 minutes after application of saline containing 0.01% pure hypochlorous acid as the preservative to the skin below the lower eyelid.

    Reviewed by Arthur B. Epstein, OD

    Phoenix—An eyelid wash preserved with pure hypochlorous acid (Avenova with Neutrox, NovaBay Pharmaceuticals) can significantly reduce the bacterial load on the surface of the eyelid. 

    Reducing the bacterial load can help reduce the signs and symptoms of dry eye, meibomian gland dysfunction (MGD), and other and other conditions related to bacterial overgrowth. 

    Related: Achieving physiologic restoration in dry eye

    “I have been using this cleaner with some of my dry eye patients who had significant lid crud, inflammation, and discomfort,” said dry eye specialist Arthur B. Epstein, OD, founder of Phoenix Eye Care and the Dry Eye Center of Arizona. “The results are disruptive. Patients see and feel the improvement in a day or two.”


    Before (left) and after (right) images of reduced bacterial load on surface of patient’s eyelid treated with the eyelid wash preserved with pure hypochlorous acid. (Photos courtesy of NovaBay Pharmaceuticals)

    Dr. Epstein was third author on a study that examined the clinical impact of the 0.01% solution of hypochlorous acid.

    Recent: Novel device provides rapid measure of tear osmolarity

    “We had good data that hypochlorous acid kills bacteria very rapidly in vitro,” added lead author David Stroman, PhD, senior vice president of ophthalmology development for NovaBay Pharmaceuticals. “We wanted data on how quickly bacteria would be removed on the eyelid in a clinical setting with patients who had significant lid inflammation.”

    Response in clinical setting

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