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    Tapping treatment paradigms for keratoconus


    Keratoconus: Treatment paradigms


    San Diego—The past 30 years have witnessed “an explosion in our knowledge of, and ability to diagnose, keratoconus,” said Prof. Charles McGhee, MD, PhD, DSc.


    The first full keratoconus paper was published in the 1800s, but is “exponentially burgeoning” in this decade, said Dr. McGhee, speaking here during World Cornea Congress.

    The long-held belief that keratoconus is non-inflammatory “may or may not be true,” he said.

    More from ASCRS 2015: Explaining explantation in foldable IOLs

    What is still held true is that the ectactic disorder “leaves scarring and hydrops, and there is no curative treatment,” said Dr. McGhee, who is in private practice in New Zealand.

    The etiology of keratoconus is multifactorial, with some suspected environmental elements.

    “The incidence ranges form 8.8 to 54.4 per 100,000, depending on the study cited,” Dr. McGhee said. “The variation is due to divergent diagnosis and exposure to cofactors.”

    Slit lamp and Placido disc have traditionally been used to diagnose the disorder. Some studies have shown more than 50% of first-degree relatives have astigmatism or abnormal cornea.

    Next: Should we be screening the general population for keratoconus?

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