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    Managing infections in artificial cornea

    Contemporary prevention, management may allay cases of keratitis, endophthalmitis

     

    When in doubt, however, these cases should be treated as infectious endophthalmitis, she said. When considering prophylaxis against infection in patients with KPro, there is no level I evidence for an ideal regimen.

    “We know that a broad-spectrum agent should be used,” Dr. Colby said. “Some investigators advocate the use of vancomycin, especially in monocular patients or those with an autoimmune disorder.”

    Recent: Researchers share ‘vision for hope’ at ARVO 2016

    Specifics about what the optimal timing and duration of the therapy, and how many times the drug should be administered daily, are still under discussion.

    Future therapeutic directions include antibiotic-eluting contact lenses or sutures, an antimicrobial coating on the KPro materials, and antibiotic-eluting synthetic corneal carrier tissue.

    Recent: Femto-CKT procedure shows promise for keratoconus stabilization

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