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    Medical, surgical advances rising to challenge of persistent epithelial defects

    Experimental approaches also showing promise for promoting corneal epithelial healing


    Take-home message: Autologous serum drops, amniotic membrane, and scleral lenses offer advanced options for management of persistent epithelial defects refractory to standard treatment modalities.


    BaltimoreAdvanced medical and surgical approaches are helping to address the challenge of treating persistent epithelial defects (PED).

    In addition, several novel investigational strategies are also showing promise for the management of this uncommon, but potentially sight-threatening condition, said Bennie H. Jeng, MD.

    In case you missed it: Toric IOLS + abnormal corneas: Do they mix?

    Conventional medical management of PED can be arduous for the ophthalmologist and a burden on the patient,” said Dr. Jeng, professor and chairman, Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore.

    “Surgical options exist when standard medical therapies fail, but several advanced treatment modalities have been proven to be very useful,” he said. “Should all else fail, experimental approaches are also under investigation and showing promise for helping our most challenging cases.”

    NEXT: A systematic approach

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