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    New dual blade can help surgeons lower IOP

    Blade targets trabecular meshwork

     

    Clinical data from eight surgeons and 122 patients who mostly had moderate or severe open-angle glaucoma revealed that in 93% of cases, trabecular meshwork was removed from the anterior chamber, Dr. Seibold said.

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    The average extent of removal was 114 degrees; in 98% of cases, surgeons said that use of the blade was easy and straightforward.

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    An analysis of post-op outcomes at three months found a 33% reduction in IOP, from 17.5 mm Hg pre-op to 11.8 mm Hg post-op. Sixty-nine percent of patients were able to stop using at least one of their glaucoma medications after surgery.

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    The strip of free tissue that is removed with the blade offers potential for future analysis, which researchers at the University of Colorado are currently considering. “We’ve never been able to take live trabecular meshwork samples of this size in glaucoma patients and study them. We can look for ultrastructural changes that may give us insight into its pathogenesis. There is also the potential for genetic analysis. We’re just on the cusp of diving in to see where this opportunity will lead us,” Dr. Seibold said.

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