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    Novel drug delivery platforms: Filling a ‘GAP’ in glaucoma


    Patient perspectives

    Patient acceptance will be an important factor influencing the adoption of alternative delivery methods. Dr. Kahook noted that data from a survey conducted at his center showed that while the majority of patients with glaucoma indicated a preference for drops over any other treatment options (including laser therapy, punctal plug drug depots, injections around or into the eye, implantable refillable reservoirs, or invasive surgery), 45% of patients said they would accept an approach more invasive than topical administration to reduce or eliminate the need for drop therapy.

    “What if a patient needs two medications?" Dr. Kahook asked. “Will patients accept replacing one drop bottle, but not the other? What happens to the patient’s risk assessment if adverse effects begin to emerge when more patients are treated and repeated injections are given?”

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