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    OCT provides minute details of aqueous outflow pathways, motion

    Platform shows collector channels open, close with pressure changes

     

    When they quantified the movements of Schlemm’s canal, collector channels, and tissue strands over time, Dr. Johnstone noted there was marked symmetry and synchrony of the various motions. The canal shape changes occurred in 100 ms and those of the collector channels in 300 ms, indicating that these structures are capable of very rapid responses.

    Dr. Johnstone explained that the opening and closing of the collector channels may act as flow-controlling resistance sites in normal eyes and sites of abnormal resistance in glaucomatous eyes. These findings may also explain the distal resistance in microinvasive glaucoma surgery.

    “Both the OCT and SEM images give me the privilege of stepping into a new world inaccessible to mankind for all these millennia,” Dr. Johnstone said. “The voyage is particularly exciting because somewhere within that wondrous world lies a solution to the pressure problem in glaucoma.”

     

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