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    Ocular perfusion pressure, cerebrospinal fluid pressure: New players in glaucoma

    The health of the retinal ganglion cells is affected by numerous factors, with intraocular pressure (IOP) being one of the most important and modifiable of the risk factors. Two additional risk factors–ocular perfusion pressure (OPP) and cerebrospinal fluid pressure (CSF)–may be instrumental in risk assessment and managing glaucoma patients.

    In discussing the involvement of OPP, Jeffrey Liebmann, MD, offered the question: “Is OPP perhaps a second modifiable risk factor in glaucoma in which only IOP is treated, and what can we do about it, if anything?”

    Dr. Liebmann is the Shirlee and Bernard Brown Professor and Director, Glaucoma Division, Harkness Eye Institute, Columbia University Medical Center, New York.


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