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    Optimizing CPC treatment outcomes with built-in transillumination

    Probe enables physicians to locate ciliary body, deliver therapy in more targeted manner

    There is a growing glaucoma pandemic, with 79.6 million people estimated to be affected by this disease by the year 2020.1 Though it is the second-leading cause of blindness, traditional therapies for glaucoma have been limited.

    Medications are often prescribed and can be effective when used properly. However, patients are well known to have issues with compliance.2
    Those with more-severe glaucoma not controlled by medication or milder laser treatments have few options and must typically undergo more invasive procedures.

    Cyclophotocoagulation (CPC) is an option that can be effective in treating glaucoma in a variety of patients by reducing aqueous secretion and thus lowering IOP. As a form of cycloablation, it is effective but often used as a last resort since it may result in the destruction of the ciliary body epithelium and stroma.3,4

    Treatment methods--such as contact transscleral cyclophotogoagulation (TSCPC) using an 810-nm, continuous-wave diode laser--have made this therapy less risky,5-9 while a more-recent laser system (Cyclo G6 Laser System using MicroPulse Transscleral Cyclophotocoagulation [mTSCPC] with the MicroPulse P3 probe, Iridex Corp.) has improved efficacy and safety even further.

    With mTSCPC, continuous wave lasers are broken into short bursts, which allows for cooling time between bursts and minimizes damage to surrounding tissue. Such treatment has been found to be very safe and effective at reducing IOP.10-13

    The treatment not only impacts aqueous inflow, but also is now thought to improve outflow as well.

    A recent study14 found that a transcleral 810-nm μP laser creates anatomic changes in the outflow pathways by inducing contractions in the ciliary muscle, which incite ciliary muscle shortening, scleral spur rotation, trabecular meshwork movement and Schlemm’s canal changes. These changes improve aqueous flow.

    To be most effective in enhancing uveoscleral outflow, the ciliary body must be precisely targeted.

    Transillumination technique

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