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    Pattern recognition receptor research yields promising results in keratitis

    New research into pattern-recognition receptors is yielding promising therapies that target the specific pathogens and inflammatory pathways in keratitis, researchers said.

    “We have reached an exciting point in the study of infectious keratitis, with so many molecular pathways being identified,” they wrote. The researchers, from three centres in Southampton, UK, published a review of these findings in the journal Eye.

    Corneal infection or inflammation causes about 1% of visual impairment worldwide, the researchers wrote, citing World Health Organisation figures.

    In the United Kingdom, the condition hospitalises 4000 people per year. Trauma caused by agrarian activity is the major cause, and studies in the United States have correlated an increase in infections with the use of contact lenses, the researcher found.

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