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    A potential new endpoint for understanding post-LASIK outcomes

    New YorkCorneal epithelial thickness has been found to remodel and change significantly after femto-LASIK, according to the findings of a prospective study conducted under the direction of A. John Kanellopoulos, MD, and colleagues.

    Specifically, corneal epithelial thickness increases in the mid-periphery, just inside the ablation zone, and the magnitude of change correlates with the amount of myopic correction.

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    The research was conducted jointly at the Laservision.gr Research and Clinical Institute, Athens, Greece, and the Department of Ophthalmology, NYU Langmore Medical School, New York, NY. It was published [J Refract Surg. 2014;30(3):16671] and presented by David Sackel, MD, who was senior resident, Department of Ophthalmology, NYU Langmore Medical Center.

    “These findings are compelling and should be taken into account when evaluating quality of vision and mesopic and scotopic issues, as the epithelial changes may affect particularly those pupillary values,” Dr. Kanellopoulos said.

    “In addition, evaluation of epithelial thickness may become an important additional measure for assessing refractive outcomes, their stability, and potential need for enhancement, particularly considering that high deviation from usual patterns in high myopic corrections that more commonly need enhancements,” Dr. Sackel said.

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