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    Predicting peripheral neuropathy in diabetes via novel eye scan

    Corneal confocal microscopy (CCM) has been found to predict peripheral neuropathy in patients with type 1 diabetes, according to a recent study.

    The new, noninvasive test involves examination of unmyelinated nerve fibers at high magnification while using a laser-scanning corneal confocal microscope to image the subbasal nerve plexus of the patient’s cornea, according to Medscape.

    The study—published online in Diabetes Care—was conducted to determine if deficits in corneal nerve fiber length assessed using CCM could predict future onset of diabetic peripheral neuropathy. 

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    The researchers compared corneal nerve fiber length and various other baseline measures between 90 nonneuropathic patients with type 1 diabetes who did and did not develop diabetic peripheral neuropathy after 4 years. The receiver operator characteristic curve was used to determine the ability of single and combined measures of neuropathy to predict diabetic peripheral neuropathy.

    Previous studies demonstrated utility for CCM in assessing peripheral diabetic neuropathy, autonomic neuropathy, and neuropathy in those with prediabetes, Medscape reported.

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    Rose Schneider Krivich
    Rose is the content specialist for Medical Economics.

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