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    Study: Not all topography devices are alike

    Haze affects post-CXL results, measurements will vary by device


    Researchers found that the thinnest corneal thickness was most variable with the Orbscan as compared with other devices.  The within-subject standard deviation and coefficient of repeatability with Orbscan showed the highest variability for all the corneal parameters in comparison with other devices.

    Among the Scheimflug, Galilei was found to be the most repeatable and in agreement for the various corneal parameters, followed by Sirius and Pentacam, Dr. Agrawal said.

    One clinical implication to keep in mind is that post-CXL, the cornea behaves differently, and the interpretation of topography should be done with caution, Dr. Agrawal said.

    “There can be subclinical haze which might not be evident on slit lamp examination,” Dr. Agrawal noted.

     Corneal haze was quantified using the densitometry software in Pentacam HR.

    Dr. Agrawal and fellow researchers are working on a correction factor that can be applied in each of the device in presence of haze.


    Aarti Agrawal, MD

    E: [email protected]

    This article was adapted from Dr. Agrawal’s presentation at the 2016 meeting of the American Society of Cataract and Refractive Surgery. Dr. Agrawal did not indicate any financial interest in the subject matter.





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