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    Study: Not all topography devices are alike

    Haze affects post-CXL results, measurements will vary by device

    Take-home message: Subclinical haze after CXL can affect corneal topography measurements; a comparison shows that measurements with four different devices cannot be used interchangeably.



    Bangalore, India—Devices used to measure corneal topography after collagen crosslinking (CXL) should not be used interchangeably, said Aarti Agrawal, MD.

    In a study, it was found that four commonly used devices had variable measurement results, and that subclinical corneal haze can affect measurements obtained with commonly used topography devices, said Dr. Agrawal, Narayana Nethralaya, Bangalore, India.

    Dr. Agrawal and fellow researchers included 60 eyes from 60 patients with keratoconus who had undergone accelerated CXL a year before. All eyes were measured with three Scheimpflug-based devices and one slit-scanning imaging device. The devices used were the Orbscan II (slit-scanning beam), Galilei G6 (Placido disk with dual Scheimpflug), Sirius (single Scheimpflug with Placido), and Pentacam HR (single Scheimpflug).

    Each eye followed a standard methodology—it was aligned to the visual axis by the central fixation light, and a single operator captured three measurements from each eye from all machines. Measurements captured were thinnest corneal thickness as well as steep (K1) and flat (K2) keratometry and astigmatism.

    Patients with previous lamellar surgery, corneal scarring, penetrating keratoplasty, and corneal ring implantation were excluded from the study.

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