/ /

  • linkedin
  • Increase Font
  • Sharebar

    Treating retinochoroiditis caused by toxomoplasis

    Two-year follow up shows benefit of trimethoprim-sulfamethoxazole

    São Paul—The use of trimethoprim-sulfamethoxazole for 2 years in patients with Toxoplasma gondii retinochoroiditis may prevent recurrences, said João Paulo Fernandes Felix, MD, Universidade Estadual de Campinas, São Paulo.

    Dr. Felix has been part of a single-center, prospective, double-masked clinical trial to compare the effects of both 1 year and 2-year treatment with trimethroprim-sulfamethoxazole to reduce the recurrence of toxoplasmosis.

    This area of research is important because ocular toxomoplasis is the main cause of infectious uveitis in the world, Dr. Felix said.

    Sponsored: Join us 8/12 in San Francisco for practical diabetic eye disease tips!

    “It’s associated with recurrent episodes of active retinal disease,” he said.

    Investigators in the study conducted their 2-year follow-up with 121 patients. For inclusion in the study, patients had to have recurrent Toxoplasma gondii retinochoroiditis and a preexisting retinochoroidal scar.Exclusion criteria included an age under 18, those who were immunocompromised or on immunosuppressive treatments, and concomitant retinochoroiditis from other causes.

    Patients received the medication twice a day for 45 days and were compared against a placebo group.

    Related: Is early anti-VEGF therapy response predictive of longer-term results?

    Recurrence rate

    New Call-to-action


    You must be signed in to leave a comment. Registering is fast and free!

    All comments must follow the ModernMedicine Network community rules and terms of use, and will be moderated. ModernMedicine reserves the right to use the comments we receive, in whole or in part,in any medium. See also the Terms of Use, Privacy Policy and Community FAQ.

    • No comments available


    View Results