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    What ARMOR update means for ocular infections

    Resistance remains high to commonly prescribed antibiotics

     

    However, she added, physicians should consider that topical vancomycin still needs to be compounded—making it off-label—and expensive and often more complex to obtain.

    In the ARMOR study, isolates from the aforementioned bacteria were collected, and susceptibility testing was performed. Researchers analyzed 441 isolates from 19 U.S. sites.

    Researchers determined minimum inhibitory concentrations by broth microdilution for up to 15 antibiotics, and then isolates were classified as susceptible or nonsusceptible.

    The ARMOR results should give physicians pause when they prescribe antibiotics, Dr. Asbell said.“Review the ARMOR data, and make it work for you,” Dr. Asbell said. “Pick the antibiotic that you think will work best for a specific patient. If you have someone who is high risk, elderly, or from a nursing home, think wisely about picking the antibiotic.”

    Bausch + Lomb initiated the ARMOR studies in 2009 to analyze antibiotic resistance for the treatment of bacterial infections. The study is the only surveillance program of its kind in the U.S. specific to monitor ocular pathogens, Dr. Asbell said.

    Studies like ARMOR provide valuable surveillance information for researchers and physicians, giving a broader view to help guide treatment choices, Dr. Asbell said.

    They also provide a wider patient sample, in contrast with smaller studies from single institutions, she added.

     

    Penny A. Asbell, MD

    E: [email protected]

    This article was adapted from Dr. Asbell’s presentation at the 2016 meeting of the Association for Research and Vision in Ophthalmology. Dr. Asbell has served on advisory boards for Bausch + Lomb.

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