Preliminary studies suggest disulfiram could aid in the treatment of mucous membrane pemphigoid (MMP). Used topically, the drug may inhibit aldehyde deydrogenase (ALDH), which plays a key role in fibrosis, wrote JK Dart, UCL Institute of Ophthalmology, London.
Only weak evidence supports the use of IOLs that filter visible blue light, researchers say. “On the basis of currently available evidence, one cannot advocate for the use of blue-light-filtering IOLs over UV-only filtering IOLs,” wroite X. Li, Waterford Institute of Technology, Waterford, Ireland, and colleagues.
Fluorescence of lens proteins could help understand, diagnose, and treat cataracts, researchers say.
“Rather than waiting for the condition to appear, it could be possible to diagnose and monitor cataract before it forms, allowing preventative measures to be taken where possible,” said Rory Duncan of Heriot-Watt University in Edinburh, United Kingdom in a press release.
Ocriplasmin (Jetrea, ThromboGenics) may achieve lower macular hole closure rates than in trials, new British and Irish data suggests. Also, “the incidence of adverse events was greater than previously reported,” wrote RJ Haynes of Bristol Eye Hospital in Bristol, United Kingdom, and colleagues in the journal Eye.