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Sulcus-to-sulcus suture technique offers solution for silicone oil use in aphakic eyes with iris loss

Retention sutures placed sulcus-to-sulcus in the iris plane are effective for keeping the silicone oil out of the anterior chamber.

Retina Treatments

New study affirms promise of anti-integrin drug for DME
New study affirms promise of anti-integrin drug for DMEA new class of ophthalmic drug continues to show promise for treating patients with diabetic macular edema (DME).
Long-term aflibercept effective for nAMD after other anti-VEGF therapies failedAflibercept (Eylea, Regeneron Pharmaceuticals) intravitreal injection, administered according to an as-needed regimen, improved the anatomic outcomes in many eyes refractory to monthly bevacizumab or ranibizumab injections that had persistent or recurrent fluid. However, half of the patients might require aflibercept injections every 4 weeks in order to achieve a completely dry retina.
Tie2 activator augments anti-VEGF for DMEResults from TIME-2, a phase IIA study, support further development of combination treatment with subcutaneous injection of the Tie2 activator, AKB-9778 (Aerpio Therapeutics), plus intravitreous (IVT) anti-VEGF injection for diabetic macular edema.
Pipeline for dry AMD features diverse compoundsA number of drugs are being investigated in clinical trials as treatment for slowing the growth of geographic atrophy that is secondary to age-related macular degeneration.
Neuroprotective treatment promising for macular telangiectasiaThe class of molecules called “neurotrophic factors” has been demonstrated to reduce the rate of photoreceptor cell loss during retinal regeneration.
Sulcus-to-sulcus suture technique offers solution for silicone oil use in aphakic eyes with iris lossPlacement of “silicone oil retention sutures” sulcus to sulcus in the iris plane in a variety of geometric patterns provides an effective method for keeping the oil out of the anterior chamber.
Two recent genetic discoveries may offer hope for patients with advanced AMDThe discovery of a gene for North Carolina macular dystrophy, PRDM13, and transplantation of induced pluripotent stem cells (iPSCs)-derived retinal cells show promise to restoring vision to patients with advanced AMD.
Consider PDGF treatment prior to anti-VEGF therapyPatients with age-related macular degeneration patients who had received anti-platelet derived growth factor (PDGF) therapy prior to anti-VEGF treatment fared better than those who did not in a pilot study.
Latest concepts in steroid therapy for diabetic macular oedemaSteroids are an important second-line treatment for the treatment of diabetic macular oedema. While side effects remain a concern, modern formulations of intravitreal steroid allow the treatment to be tailored to the individual patient.
Advancing diagnostics and detection of neovascular age-related macular degenerationEarly detection and treatment is essential to preserve vision in patients with age-related macular degeneration. A new device, the ForeseeHome®, uses preferential hyperacuity perimetry for early detection of choroidal neovascularisation before symptoms develop.